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Focal actin variable keratin negative s100 negative desmin negative genetic studies t(17;22) with fusion of col1a1 and pdgfb in all cases tested differential diagnosis dermatofibroma / dermal fibrous histiocytoma myxoid nerve sheath tumor myxoid liposarcoma plexiform fibrohistiocytic tumor desmoplastic melanoma fibrosarcoma dermal and deep fibrous histiocytoma dermatofibrosarcoma protuberans usually <1 cm frequently >2 cm haphazard short fascicles in dermal lesions; deep lesions frequently storiform regular storiform pattern infrequent infiltration into and around fat cells frequent infiltration into and around fat cells frequently mixed cell population monomorphous cell population frequent overlying epithelial hyperplasia overlying epithelium usually attenuated cd34 40% in deep lesions, negative in dermal lesions cd34 100% extensive apolipoprotein d negative (deep lesions not tested) apolipoprotein d 90% factor xiiia >95% extensive factor xiiia 75% but focal and weak cd34 and factor xiiia are difficult to interpret in many cases because of numerous entrapped reactive cells   myxoid nerve sheath tumor myxoid dermatofibrosarcoma protuberans areas of typical nerve sheath tumor usually present areas of typical storiform pattern usually present s100 positive s100 negative cd34 may stain scattered dendritic cells but not lesional cells cd34 stains lesional cells   myxoid liposarcoma myxoid dermatofibrosarcoma protuberans usually involves deep soft tissue usually involves dermis and superficial subcutaneous tissue frequently contains lipoblasts no lipoblasts cd34 may stain scattered dendritic cells but not lesional cells cd34 stains lesional cells   plexiform fibrohistiocytic tumor dermatofibrosarcoma protuberans ray-like extension into surrounding fat infiltrates between and around individual fat cells collagenous stroma usually contains only fine collagen nodules of histiocytes and giant cells in most cases histiocytes and giant cells very rare cd34 negative cd34 stains lesional cells     desmoplastic melanoma dermatofibrosarcoma protuberans lacks storiform pattern prominent storiform pattern displaces or destroys fat infiltrates between and around individual fat cells dense collagenous stroma usually contains only fine collagen frequently contains lymphoid nodules inflammatory cells infrequent cd34 negative cd34 stains lesional cells s100 positive s100 negative   dermatofibrosarcoma protuberans adult or infantile fibrosarcoma cd34 positive cd34 negative stor. viagra canada pharmacy Viagra side effects rash viagra women cream viagra generic viagra buy viagra online buy generic viagra camille paglia new york times viagra viagra one time cheap viagra Natural alternatives to viagra for women cheap viagra without prescription buy generic viagra viagra generic viagra over the counter viagra at walmart buy viagra cheap viagra generic canadian viagra buy online buy cheap viagra cheap viagra fast shipping overnight How to use viagra safely viagra generic viagra viagra goes generic in march  

 

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